Понедельник, 1 июля 2013, 18.00
МГУ, Лаб. корпус Б (факультет биоинженерии и биоинформатики), к. 221.
Seattle Children's Research Institute
Proteomes in Profile
These days, large volumes of high-throughput mass spectrometry
proteomics studies are routinely conducted. The studies are ultimately
aimed at better understanding biological processes by studying
proteomes' profiles. However, the size and complexity of proteomics data
hinders efforts to easily share, integrate, query, and compare such
profiles. We will overview our recent developments addressing these
challenges, including the creation of MOPED (Model Organism Protein
Expression Database, moped.proteinspire.org). MOPED focuses on answering
four fundamental questions:
1. Which proteins are identified and where (organisms, tissues, localizations, pathways)?
2. How much of each protein is identified (relative and absolute expression)?
3. How does the knowledge of your current experiment compare to existing information?
4. How does this knowledge guide your next (experimental or computational) study?
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